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Recommendations for Contraceptive Use

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Combined Oral Contraceptives (COCs)


Classification of Selected Procedures for Low Estrogen Combined Oral Contraceptives (COCs)

Procedure Class Rationale
Pelvic examination (speculum and bimanual) C
  • Conditions which would restrict use of COCs should be identified by history before method initiation.
  • A pelvic exam may reveal reproductive tract infections or reproductive tract malignancies which should be treated for optimal preventive care. Routine pelvic exam screening for asymptomatic women, in the absence of tests for cervical cancer, however, is a low yield procedure1.
  • A pelvic exam may help evaluate the question of pregnancy: in this case it is Class A.
  • A pelvic exam is not necessary to ensure safe use of COCs as a contraceptive method.
Blood pressure B
  • Due to their estrogen component, COCs have subtle (and usually insignificant) effects on blood pressure 2. Where possible, for clients at risk of high blood pressure, blood pressure screening would ideally accompany initiation of COCs.
  • Women with a long history of severe hypertension are at high risk of vascular disease, and thus arterial thrombosis (clotting), which estrogens may worsen.
Breast examination B Lumps that are suspicious for cancer should be evaluated. While any hormonal treatment may in theory cause such lumps to grow3, pregnancy causes much higher hormonal levels; therefore, a potential malignancy of the breast should not be a reason to delay a woman's access to the use of this contraceptive method.
STD screening by lab tests (for asymptomatic persons) C For optimal health care, clients at risk for STDs (by personal history or socio-demographic risk factors) should be offered STD screening where possible. However, presence of an STD will not affect the safe use of COCs.
Cervical cancer screening C Cervical cancer screening is indicated for women at risk of cervical carcinoma, and is recommended (where possible) for optimal preventive health care for women of reproductive age or beyond (particularly women at risk of STDs).

NOTE:Though causality has not been established, long-term (more than 5 years) COC use may be associated with a slight increased risk of cervical cancer4,5. Cervical cancer screening is advised for optimal preventive care for all women at risk of cervical cancer (e.g., smokers, women with partners having multiple partners, women with young age at first intercourse, etc.4,5). All women at risk should ideally have access to a practical method of cervical cancer screening, treatment and follow-up.

Routine, mandatory lab tests (e.g., cholesterol, glucose, liver function tests) D The effects of COCs on cholesterol, blood glucose and normal liver function are slight, and of no demonstrated clinical significance6.
Specific counseling points for COC use:
  • efficacy
  • common side effects
  • correct use of method (including instructions for missed pills)
  • signs and symptoms for which to see a health provider
  • STD protection (when/as appropriate)
A
  • Accurate client education is essential for maximum quality of family planning services.
  • Appropriate counseling about common contraceptive side effects at the time of method selection can lead to improved client satisfaction and contraceptive continuation7.
Counseling concerning change in menses, including irregular or absent menstrual bleeding A Low dose COCs commonly cause "breakthrough bleeding" (spotting or bleeding during the three weeks of active pills), especially in the first three months of COC use. Low dose COCs also commonly cause very light menses, and amenorrhea (absence of withdrawal bleeding) may occur.

KEY:

Class A = essential and mandatory or otherwise important in all circumstances, for safe and effective use of the contraceptive method

Class B = medically/epidemiologically rational in some circumstances to optimize the safe and effective use of the contraceptive method, but may not be appropriate for all clients in all settings

Class C = may be appropriate for good preventive health care, but not materially related to safe and effective use of the contraceptive method

Class D = not materially related to either good routine preventive health care or to the safe and effective use of the contraceptive method

Citations:

Huber DH, Huber SC. Screening oral contraceptive candidates and inconsequential pelvic examinations. Studies in Family Planning 1975;6(2):49-51.

Task Force on Oral Contraceptives, WHO Special Programme of Research, Development and Research Training in Human Reproduction. The WHO Multicentre trial of the vasopressor effects of combined oral contraceptives: Comparisons with IUD. Contraception 1989;40:129-145.

Droegemueller W. Breast Diseases, in Herbst AL, Mishell DR, Stenchever MA, Droegemueller W (eds). Comprehensive Gynecology, 2nd edition. St. Louis, Mosby Year Book, 1992, pp 377-408.

Brinton LA. Oral contraceptives and cervical neoplasia. Contraception 1991;43(6):581-595.

Schlesselman JJ. Oral contraceptives in relation to cancer of the breast and reproductive tract - an epidemiological review. British Journal of Family Planning 1989;15:23-33.

Speroff L, Glass RH and Kase NG. Clinical Gynecologic Endocrinology and Infertility, 5th edition. Baltimore, Williams and Wilkins, 1994, pp 726-727.

Cotten N, Standback J, Maidouka H, Taylor-Thomas JT, Turk T. Early discontinuation of contraceptive use in Niger and The Gambia. International Family Planning Perspectives 1992;18(4):145-149.


Any part of Recommendations for Updating Selected Practices in Contraceptive Use may be reproduced or adapted to meet local needs without prior permission from the TG/CWG Secretariat, provided the TG/CWG is acknowledged and the material is made available free of charge or at cost.


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