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a) Male condoms should be put on after erection and before genital and/or anal contact.
b) The female condom should be put into place any time before the penis touches the vagina in order to prevent exposure to pre-ejaculate and semen.
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a-b) Although viable sperm are generally absent from pre-ejaculatory fluid, human immunodeficiency virus (HIV) is present in the pre-ejaculate of HIV-positive men. Thus the pre-ejaculate may transmit disease, and the condom should be in place before genital contact occurs.
- Ilaria G, Jacobs JL, Polsky B, Koll B, Baron P, MacLow C, et al. Detection of HIV-1 DNA sequences in pre-ejaculatory fluid (letter). Lancet 1992;340:1469.
- Pudney J, Oneta M, Mayer K, Seage G III, Anderson D. Pre-ejaculatory fluid as potential vector for sexual transmission of HIV-1 (letter). Lancet 1992;340:1470.
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