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Cross-Sectional Study of Bone Density in Long-Term Users of DMPA8
Abstract: In 1991 Cundy et al
(New Zealand) reported that long-term DMPA users (more than 1 to 2 years) experienced a
significant loss in bone density. The design of that study was flawed, however, and
variance in the measurements was very high (in many cases, greater than the differences in
the measured loss). Until this new (1995) paper was published there was no evidence to
refute these findings. In the present cross-sectional study of long-term users of DMPA who
were amenorrheic or only spotting for more than 1 year, spine and femoral neck bone
density was measured and compared to that of an age-matched population of nonDMPA users.
Based on the preliminary results, the authors found no significant changes in spinal or
femoral neck bone density (measured as 9899.5% of that of the age-matched
population). Because the youngest subject was 21, however, this study does not shed any
light on the question of possible bone loss in DMPA users who are very youngages 13
to 16. (This is the time period when the rate of bone deposition is greatest, and the
potential effect of changes in bone metabolism also could be the greatest.)
8 Gbolade BA and RJE Kirkman. University of
Manchester: Manchester, England. (Abstract presented at the meeting of the Society for the
Advancement of Contraception, Guatemala City, Guatemala, March 1995.)
Comparison Between Standard and
U Techniques for Norplant Implants Removal9
Abstract: In this paper, Dr.
Untung presented new data comparing the U technique with the standard removal
method. These data indicated that with the U technique, the time for removal
was less, fewer capsules were broken and there was less tissue trauma (i.e., fewer clients
with postremoval hematoma: 2.44% versus 9.76%). A recently published JHPIEGO technical
report concludes that the U technique appears to be more easily learned by
inexperienced, novice removers than the standard technique for implants removal. In
addition, the U technique appears to offer significant improvements in speed
and safety over the standard technique recommended by the manufacturer without any
significant increase in cost. This technical report recommends that large-scale training
programs should consider using the U technique as the removal method of choice
when training new providers in implants removal.10
(Investigators agree that correct insertion of the capsules is the single most important
factor in making removal easy.)
9 Praptohardjo U. Department of Obstetrics and
Gynecology, Medical Faculty Diponegoro University, Dr. Kariadi Hospital, Semarang,
Indonesia. (Abstract presented at the meeting of the Society for the Advancement of
Contraception, Guatemala City, Guatemala, March 1995.)
10 Blumenthal et al. 1996. Comparative Assessment of
Norplant® Implants Removal Techniques: Indonesia. JHPIEGO Technical Report FCA-22.
JHPIEGO: Baltimore, Maryland, USA.
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