Over and above the oral route of delivering combined hormonal contraceptives, researchers
have developed a few methods with alternative routes of hormone delivery. This
has been to avoid hepatic first pass metabolism and daily intake of hormones. The combined hormonal contraceptive methods introduced recently include:
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Yasmina combined oral contraceptive pill with a newer progestin,
Drospirenone,
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Nuva Ringa contraceptive vaginal ring,
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Ortho Evraa transdermal contraceptive patch, and
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Lunellea monthly injectable contraceptive.
All of these methods contain both estrogen and progesterone with daily dosage either less than or
the same as in combined oral contraceptive pills. The mechanism of action, advantages and limitations, indications and precautions for use, side effects and complications, and the time for starting these methods are similar to
combined oral contraceptive pills, with a few exceptions.