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Recommendations for Contraceptive Use

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Combined Oral Contraceptives (COCs)

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Q.1. When is the best time to start COCs?

Recommendations

Rationales

a) COCs may be started any time you can be reasonably sure that the woman is not pregnant, for example, during the 7 days which begin with the onset of menses (days 1 through 7 of the menstrual cycle).

(See Q.2. for postpartum initiation and Q.3. for post-abortion initiation.)

a) Starting within the first 7 days lowers the possibility of beginning the pill while she is already pregnant (although there is the possibility that the client is pregnant and implantation bleeding has been mistaken for menses).
  1. Dixon GW, Schlesselman JJ, Ory HW, Blye RP. Ethinyl estradiol and conjugated estrogens as postcoital contraceptives. Journal of the American Medical Association 1980;244:1336-1339.
  2. Gray RH, Pardthaisong T, McDaniel EB, Doyle P. The timing of the first injection of Depo Provera. IPPF Medical Bulletin 1975;9(3):3-4.
  3. Schiphorst LE, Collins WP, Roystar JP. An estrogen test to determine the times of potential fertility in women. Fertility and Sterility 1985;44:328-334.
   
b) For a woman having menstrual cycles, no back-up method is needed if she is in the first 7 days of her menstrual cycle and is still menstruating. If she is in the first 7 days of her cycle, but is not menstruating, some programs may recommend use of a back-up method for 1 week.

COCs may be started anytime you can be reasonably sure the woman is not pregnant. However, if COCs are started after day 7 of a regular cycle, the woman should also be counseled that:

  • her regular bleeding pattern may be altered, and
  • a back-up method (or abstinence) should be used for 7 days.

(For information concerning need for back-up method see COCs Q.7.)

b) A back-up method is NOT needed if the first package of pills is started while the woman is menstruating because the risk of conception is virtually nil.
  • After day 5 of the cycle, the risk of pregnancy begins to rise.
  1. Smith SK, Kirkman RJE, Arce BB, McNeilly AS, Loudon NB, Baird DT.

The effect of deliberate omission of Trinordiol® or Microgynon® on the hypothalamo-pituitary-ovarian axis. Contraception 1986;34(5):513-522.

Some programs might recommend a back-up method for women who are not menstruating at the time of COC initiation because there is a very slight risk of conception from unprotected intercourse on day 7 of the cycle.

When back-up (or abstinence) is needed, it must be used for 7 days because 7 days of exposure to COCs are required to suppress follicular development.

  1. Molloy BG, Coulson KA, Lee JM, Watters JK. "Missed pill" conception: fact or fiction? British Medical Journal 1985;290:1474-1475.
   
c) If the client is using the 28-day pill packet, she should start a new packet the day after she finishes the previous packet (without a break). If the client is using the 21-day pill packet, she should skip 7 days before starting a new packet. If the pills are taken correctly, the client will always begin a new packet on the same day of the week. c) The longer the pill-free interval, the higher the risk of ovulation (e.g., a 10-day pill free interval confers a 10% risk of ovulation).
  1. Landgren BM, Emiczky CS. The effect on follicular growth and luteal function of "missing the pill." Contraception 1991; 43(2):149-159.
  2. Killick SR, Bancroft K, Oelbaums MJ, Elstein M. Extending the duration of the pill-free interval during combined oral contraception. Advances in Contraception 1990;6:33-40.

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Any part of Recommendations for Updating Selected Practices in Contraceptive Use may be reproduced or adapted to meet local needs without prior permission from the TG/CWG Secretariat, provided the TG/CWG is acknowledged and the material is made available free of charge or at cost.


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